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A large study (over 500 families) in Vancouver and Winnipeg of early developmental interventions to modify the expression of allergy and asthma in high-risk children that started in 1996 has completed the seventh year evaluations. Current results show a 56 per cent reduction in asthma development in children who are now of school age.
In 2004 an epidemiologic study of the prevalence of asthma and allergic disease was undertaken in Vancouver of more than 3,000 children aged 12-14 years. This was part of the International Study of Asthma and Allergy in Children Phase 3. Participation of students was 95 per cent; almost double that of elsewhere in Canada. The data are currently being analyzed.
During the last five years, two large-scale randomized clinical trials have been conducted examining the safety of inhaled corticosteroids in children with asthma, and a third examined the efficacy and safety of adding long-acting beta-agonist therapy to regular inhaled corticosteroids in children.