Patients who have two readings of tTG > 10 ULN (spaced by 1 month) are considered to meet non-biopsy diagnosis criteria for celiac disease with an accuracy of > 95% . Referred patients will be reviewed by our dietitians and teachings related to gluten free diet will take place.
Patients with tTG > 2 ULN and < 10 ULN should still go on to have upper endoscopy and biopsies. It is important these patients remain on a gluten containing diet.
Patients with tTG readings < 2 ULN should should be followed with serial readings and should not implement a gluten free diet
NAPSGHAN Clinical Report on the Diagnosis and Treatment of Gluten related Disorders - JPGN 2016
NASPGHAN - Diagnosis and Treatment of Celiac Disease in Children - Clinical Practice Guideline Summary -